“How do our experiences transform into learning & memory?”
The Neuron Signaling Laboratory is a young research group led by Dr. Siew Cheng (Andrea) Phua in the Department of Biological Sciences at the National University of Singapore. We are also part of the NUS Centre for Bioimaging Sciences and LSI Neurobiology Programme. Research projects in our laboratory are primarily driven by the curiosity to understand how our experiences transform into learning and memory. We are investigating molecular to systems functions of the neuronal cilium and nucleus in reward and fear learning, by applying advanced molecular, imaging and computational approaches in vivo. By illuminating the cell biology in behaving brain, we hope to gain deeper knowledge of how cognitive processes take form & seek for better ways to improve learning in normal & pathological states.
-Lab lunch at The Royals Bistro, Feb 10th 2025-
Current Research Projects:
Investigating how neuronal cilia in striatum influence goal-directed learning processes
Computationally decoding striatal gene and neural activity dynamics during goal-directed learning
Unraveling the signaling function of axon-cilium synapses in the brain
Investigating how amygdala neurons re-purpose oncogenic signaling in encoding anxiety
Unraveling how primary cilia entrain circadian rhythm on anxiety
Investigating biological factors influencing motor neuronal ensemble formation
We welcome postdocs, undergraduate & graduate students to join our team; please write in to us to find out more.
The views and opinions expressed herein are those of the author(s) and do not represent the views and opinions of the National University of Singapore or any of its subsidiaries or affiliates